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Health-related quality of life in patients with pharyngeal carcinoma: A five-year follow-up.

På svenska

Author

  • Mats Nordgren
  • Magnus Jannert
  • Morten Boysen
  • Marianne Ahlner-Elmqvist
  • Ewa Silander
  • Kristin Bjordal
  • Eva Hammerlid

Summary, in English

Purpose. The purpose was to evaluate the health-related quality of life (HRQL) of patients with pharyngeal carcinoma at diagnosis and after 1 and 5 years in relation to tumor location and treatment modality in a prospective multi-center study. Methods. Eighty-nine patients with pharyngeal carcinoma (mean age, 60.0 years; 76% men) were evaluated using the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Core 30 (EORTC QLQ-C30) and the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Head and Neck Cancer Module (EORTC QLQ-H&N35). Results. Problems with dry mouth and teeth became worse between diagnosis and the 5-year follow-up. Problems with thick secretions and teeth increased between 1 and 5 years. The HRQL at diagnosis was associated with survival. Patients with oropharyngeal carcinoma reported better HRQL than patients with hypopharyngeal carcinoma. Conclusions. For patients with pharyngeal carcinoma, the HRQL at diagnosis seems to be an important factor for the prognosis of both HRQL over time and survival. Treatment of pharyngeal carcinoma often results in long-term side effects such as dry mouth, problems with teeth, and thick secretions. (c) 2005 Wiley Periodicals, Inc.

Publishing year

2006

Language

English

Pages

339-349

Publication/Series

Head and Neck

Volume

28

Issue

Nov 14

Document type

Journal article

Publisher

John Wiley & Sons Inc.

Topic

  • Surgery
  • Otorhinolaryngology

Keywords

  • pharyngeal carcinoma
  • longitudinal HRQL
  • EORTC QLQ-C30
  • predictive factors
  • EORTC
  • OLO-H&N35

Status

Published

Research group

  • Laryngoesophagology, Allergy and Life Quality

ISBN/ISSN/Other

  • ISSN: 1043-3074