Robustness of metabolic maps
Author
Summary, in English
With the ever increasing amount of genomic data available, the interest for generating biochemical pathways has grown tremendously. So far, mainly complete genomes have been used to reconstruct the biochemical pathways and their associated interactions. However, a large number of low coverage genomes, as well as other sources of partial genomic data, are currently available for many organisms. In order to be able to use incomplete data for metabolic reconstruction, the inherent properties of this procedure need to be investigated. In this short note, we describe the robustness and predictive power of metabolic reconstructions using partial information from Schizosaccharomyces pombe. We also discuss the implications of the results on reference genome projects as well as other large-scale sequencing data.
Department/s
Publishing year
2004
Language
English
Pages
589-593
Publication/Series
Journal of Bioinformatics and Computational Biology
Volume
2
Issue
3
Document type
Journal article
Publisher
World Scientific Publishing
Topic
- Biological Sciences
Keywords
- Metabolic reconstructionmetabolic mapsgenome analysisrobustness analysisbiochemical pathways
Status
Published
Research group
- Microbial Ecology
ISBN/ISSN/Other
- ISSN: 0219-7200