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Enhetliga analyser av narkotika i urin krävs för rättssäkerheten.

På svenska

Author

  • Therese Hansson
  • Anders Helander
  • Olof Beck
  • Anders Elmgren
  • Fredrik Kugelberg
  • Robert Kronstrand

Summary, in English

Drugs of abuse testing is used in various areas of society for detection and follow-up of drug use. In routine laboratory drug testing, immunoassays are employed for initial screening of specimens to indicate the presence of drugs. To confirm a positive screening test, a secondary analysis by mass spectrometry is performed. The »cut-off« is the pre-defined concentration threshold of a drug or drug metabolite above which the sample is considered positive. A reading below this level implies a negative test result. Swedish drug testing laboratories currently employ varying cut-offs to distinguish between a positive and a negative test result. Because a positive drug test may have serious legal consequences to the individual, it is of importance that testing is performed and judged equally, regardless of where it is performed. A national harmonization of cut-offs is therefore warranted. Based on data from four major Swedish drug testing laboratories, and considering the recommendations in international guidelines, a proposal for national harmonization of urine cut-offs for the most common set of drugs of abuse is presented.

Publishing year

2015

Language

Swedish

Publication/Series

Läkartidningen

Volume

112

Document type

Journal article

Publisher

Swedish Medical Association

Topic

  • Medicinal Chemistry

Status

Published

ISBN/ISSN/Other

  • ISSN: 0023-7205