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Neosordarin and hydroxysordarin, two new antifungal agents from Sordaria araneosa

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Author

Summary, in English

Two novel antifungal agents belonging to the sordarin family have been isolated from fermentations of Sordaria araneosa by bioassay-guided purification and their structures elucidated by NMR techniques. Neosordarin (1) is closely related to the recently discovered hypoxysordarin (2), with only small differences on the aliphatic side chain acylating the hydroxyl in the 3'-position of the sordarose moiety. Hydroxysordarin (3) closely resembles sordarin (4), the only slight difference being the replacement of sordarose with altrose as the sugar unit.

Publishing year

2002

Language

English

Pages

377-382

Publication/Series

Journal of Antibiotics

Volume

55

Issue

4

Document type

Journal article

Publisher

Japan Antibiotics Research Association

Topic

  • Organic Chemistry

Status

Published

ISBN/ISSN/Other

  • ISSN: 0021-8820