The browser you are using is not supported by this website. All versions of Internet Explorer are no longer supported, either by us or Microsoft (read more here: https://www.microsoft.com/en-us/microsoft-365/windows/end-of-ie-support).

Please use a modern browser to fully experience our website, such as the newest versions of Edge, Chrome, Firefox or Safari etc.

Automatic individualized contrast medium dosage during hepatic computed tomography by using computed tomography dose index volume (CTDIvol)

På svenska

Author

  • Anders Svensson
  • Jonas Björk
  • Kerstin Cederlund
  • Peter Aspelin
  • Ulf Nyman
  • Torkel B. Brismar

Summary, in English

To compare hepatic parenchymal contrast media (CM) enhancement during multi-detector row computed tomography (MDCT) and its correlation with volume pitch-corrected computed tomography dose index CTDIvol) and body weight (BW). One hundred patients referred for standard three-phase thoraco-abdominal MDCT examination were enrolled. BW was measured in the CT suite. Forty grams of iodine was administered intravenously (iodixanol 320 mg I/ml at 5 ml/s or iomeprol 400 mg I/ml at 4 ml/s) followed by a 50-ml saline flush. CTDIvol presented by the CT equipment during the parenchymal examination was recorded. The CM enhancement of the liver was defined as the attenuation HU of the liver parenchyma during the hepatic parenchymal phase minus the attenuation in the native phase. Liver parenchymal enhancement was negatively correlated to both CTDIvol (r = -0.60) and BW (r = -0.64), but the difference in correlation between those two was not significant. CTDIvol may replace BW when adjusting CM doses to body size. This makes it potentially feasible to automatically individualize CM dosage by CT. aEuro cent CTDI (vol) is related to liver CM enhancement in the parenchymal phase. aEuro cent CTDI (vol) provides comparable information to body weight (BW). aEuro cent CTDI (vol) may be used when automatically adjusting CM dose for patient size.

Publishing year

2014

Language

English

Pages

1959-1963

Publication/Series

European Radiology

Volume

24

Issue

8

Document type

Journal article

Publisher

Springer

Topic

  • Radiology, Nuclear Medicine and Medical Imaging

Keywords

  • Computed tomography
  • Contrast media
  • Injection protocol
  • Radiation dose

Status

Published

ISBN/ISSN/Other

  • ISSN: 0938-7994