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Airway epithelial repair: breathtakingly quick and multipotentially pathogenic

På svenska

Author

Summary, in English

Epithelial shedding, even to the point of airway denudation, had already been described as a common and unifying feature of asthma by the latter half of the 19th century. However, the repair processes that specifically follow the shedding-like loss of epithelial cells have only recently been examined in vivo. This paper discusses the exceedingly fast epithelial restitution and the potential pathogenic sequelae to epithelial shedding alone that have been unravelled. Epithelial cytoprotection emerges as an important property of future therapeutic drugs for the treatment of airways inflammatory conditions.

Publishing year

1997

Language

English

Pages

1010-1012

Publication/Series

Thorax

Volume

52

Issue

11

Document type

Journal article

Publisher

BMJ Publishing Group

Topic

  • Respiratory Medicine and Allergy

Keywords

  • asthma pathology
  • mucosal barrier
  • epithelial repair

Status

Published

Research group

  • Airway Inflammation and Immunology

ISBN/ISSN/Other

  • ISSN: 1468-3296