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Acetate formation and dissolved oxygen responses to feed transients in Escherichia coli fermentations: Modeling and experiments

På svenska

Author

Summary, in English

Two hypotheses for acetate formation in <em>Escherichia coli</em> are used to obtain relations between glucose uptake, oxygen uptake and acetate production. Based on these relations, models for dissolved oxygen responses to feed rate transients are derived. Simulations of the models are compared with experimental data. It is shown that information about acetate production can be obtained from the dissolved oxygen measurement by making short pulses in the feed rate.

Publishing year

1998

Language

English

Document type

Conference paper

Topic

  • Bioprocess Technology
  • Control Engineering

Keywords

  • Dynamic model
  • acetate
  • dissolved oxygen
  • transients
  • Escherichia coli.

Conference name

7th International Conference on Computer Applications in Biotechnology

Conference date

1998-06-15

Conference place

Osaka, Japan

Status

Published