Factor H Autoantibodies in Patients with Antiphospholipid Syndrome and Thrombosis.

Summary, in English

Autoantibodies to complement factor H (FH) are associated with atypical hemolytic uremic syndrome, but can also be detected in patients with rheumatoid arthritis and in patients positive for lupus anticoagulants and thus potentially antiphospholipid syndrome (APS). To our knowledge, no data are available on the association between the presence of FH autoantibodies in APS and clinical manifestations.

• Author: Anna Foltyn Zadura; Ashfaque Memon; Ljudmila Stojanovich; Carlo Perricone; Fabrizio Conti; Guido Valesini; Gordana Bogdanovic; Andreas Hillarp; Yehuda Shoenfeld; Jan Sundquist; Jonatan Leffler; Peter Svensson; Leendert Trouw; Anna Blom
• Department/s: Protein Chemistry, Malmö; Family Medicine and Clinical Epidemiology; Clinical Chemistry, Malmö; Clinical Coagulation, Malmö; EpiHealth: Epidemiology for Health
• Publishing year: 2015
• Language: English
• Pages: 1786-1793
• Publication/Series: Journal of Rheumatology
• Volume: 42
• Issue: 10
• Links: http://www.ncbi.nlm.nih.gov/pubmed/26276971?dopt=Abstract; http://dx.doi.org/10.3899/jrheum.150185
• Document type: Journal article
• Publisher: Journal of Rheumatology Publishing Company Limited
• Topic: Rheumatology and Autoimmunity
• Status: Published
• Project: Genetic risk factor of venous thromboembolism and its recurrence; Identification of diagnostic and prognostic biomarkers of venous thromboembolism and its recurrence
• Research group: Protein Chemistry, Malmö; Family Medicine and Clinical Epidemiology; Clinical Chemistry, Malmö; Clinical Coagulation, Malmö
• ISBN/ISSN/Other: ISSN: 0315-162X