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Longitudinal three-dimensional visualisation of autoimmune diabetes by functional optical coherence imaging.

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Author

  • Corinne Berclaz
  • Anja Schmidt-Christensen
  • Daniel Szlag
  • Jerome Extermann
  • Lisbeth Hansen
  • Arno Bouwens
  • Martin Villiger
  • Joan Goulley
  • Frans Schuit
  • Anne Grapin-Botton
  • Theo Lasser
  • Dan Holmberg
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Summary, in English

It is generally accepted that structural and functional quantitative imaging of individual islets would be beneficial to elucidate the pathogenesis of type 1 diabetes. We here introduce functional optical coherence imaging (FOCI) for fast, label-free monitoring of beta cell destruction and associated alterations of islet vascularisation.

Department/s

  • Autoimmunity

Publishing year

2015-11-27

Language

English

Publication/Series

Diabetologia

Document type

Journal article

Publisher

Springer

Topic

  • Radiology, Nuclear Medicine and Medical Imaging

Status

Published

Project

  • inflammatory events leading to autoimmune Diabetes

Research group

  • Autoimmunity

ISBN/ISSN/Other

  • ISSN: 1432-0428