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Optical coherence tomography in clinical examination of non-pigmented skin malignancies

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Author

Editor

  • W Drexler

Summary, in English

Optical coherence tomography (OCT) images of basal cell carcinomas (BCCs) have been acquired using a compact handheld probe with an integrated video camera allowing the OCT images to be correlated to a skin surface image. In general the healthy tissue of the skin has an obvious stratified structure, whereas the cancerous tissue shows a more homogenous structure. Thus it was demonstrated that it is possible to distinguish BCCs from healthy tissue by means of OCT. Furthermore different histological types of BCC were identified. Comparison of OCT images taken prior to and immediately after photodynamic therapy clearly shows the tissue response to the treatment, and indicates local oedema in the treated area.

Department/s

Publishing year

2003

Language

English

Pages

160-167

Publication/Series

OPTICAL COHERENCE TOMOGRAPHY AND COHERENCE TECHNIQUES

Volume

5140

Document type

Conference paper

Publisher

SPIE

Topic

  • Atom and Molecular Physics and Optics

Conference name

Optical Coherence Tomography and Coherence Techniques Conference, MUNICH, GERMANY, JUN 22-24, 2003

Conference date

0001-01-02

Status

Published

ISBN/ISSN/Other

  • ISSN: 1996-756X
  • ISSN: 0277-786X
  • ISBN: 0-8194-5010-3