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Synthesis of decaline analogues of isovelleral

På svenska

Author

  • Martin H Johansson
  • I Aujard
  • Daniel Röme
  • H Anke
  • Olov Sterner

Summary, in English

Decaline analogues of the bioactive fungal sesquiterpene (+)-isovelleral (1a), retaining the bicyclo[4,1,0]hept-2-en-1,2-dicarbaldehyde system, were prepared, and their cytotoxic and antimicrobial activities were compared with those of the natural product. While the two isomers (+/-)-2 and (+/-)-3 were as active as isovelleral (1a), the isomer (+/-)-4 was approximately 10 times less potent.

Publishing year

2005

Language

English

Pages

984-989

Publication/Series

Zeitschrift fuer Naturforschung. Section B: A Journal of Chemical Sciences

Volume

60

Issue

9

Document type

Journal article

Publisher

Verlag der Zeitschrift für Naturforschung

Topic

  • Organic Chemistry

Status

Published

ISBN/ISSN/Other

  • ISSN: 0932-0776