The browser you are using is not supported by this website. All versions of Internet Explorer are no longer supported, either by us or Microsoft (read more here: https://www.microsoft.com/en-us/microsoft-365/windows/end-of-ie-support).

Please use a modern browser to fully experience our website, such as the newest versions of Edge, Chrome, Firefox or Safari etc.

Influence of factor V Leiden on the development of neovascularisation secondary to central retinal vein occlusion.

På svenska

Author

Summary, in English

Aims: To investigate if the presence of factor V Leiden has an influence on the prognosis in central retinal vein occlusion (CRVO).



Methods: 166 patients with CRVO were studied retrospectively. They were tested for factor V Leiden using DNA analysis. The presence of the mutation was studied in correlation with the development of neovascular complications 1 year after the thrombotic event.



Results: 56 of 166 patients (34%) developed neovascular complications after 1 year. In the patients who had the studied mutation 11 of 20 (55%) had developed neovascular complications after 1 year, compared to 45 of 146 patients (31%) in the group without factor V Leiden (p=0.04).



Conclusion: The presence of factor V Leiden seems to enhance the risk of developing neovascular complications in CRVO.

Publishing year

2003

Language

English

Pages

305-306

Publication/Series

British Journal of Ophthalmology

Volume

87

Issue

3

Document type

Journal article

Publisher

BMJ Publishing Group

Topic

  • Ophthalmology
  • Medicinal Chemistry

Status

Published

Research group

  • Clinical Chemistry, Malmö

ISBN/ISSN/Other

  • ISSN: 1468-2079