Immunome: a reference set of genes and proteins for systems biology of the human immune system.
Author
Summary, in English
The function of the immune system requires coordinated expression and action of many genes and proteins. With the emergence of high throughput technologies it has become possible to target human immunity from a systems biology point of view. To perform systems biology studies with comparable results we need not just a reference gene and protein set but also useful and descriptive reference categories for the immunity related genes. We have identified and collected the genes and proteins of the essential human immunome. The 847 genes and proteins were annotated, and characterized, and they were categorized according to their functions, protein domains and Gene Ontology terms. The reference set and the categories are freely available in the immunome database at http://bioinf.uta.fi/Immunome/.
Publishing year
2006
Language
English
Pages
87-89
Publication/Series
Cellular Immunology
Volume
244
Issue
2
Links
Document type
Journal article
Publisher
Elsevier
Topic
- Medical Genetics
Keywords
- Immune System: physiology
- Immunity: genetics
Status
Published
ISBN/ISSN/Other
- ISSN: 0008-8749