Economic evaluation of the hydrolysis of lactose using immobilized beta-galactosidase
Author
Summary, in English
A computer program for preliminary cost estimates of free and immobilized enzyme systems has been developed. The cost for the hydrolysis of lactose by β-galactosidase fromAspergillus oryzae has been calculated for a batch tank reactor, with free (BTRF) and immobilized (BTRI) enzymes, a continuously stirred tank reactor (CSTR) and a plug-flow tubular reactor (PFTR), considering the mass transfer behavior and deactivation of the enzyme.
Enzyme immobilization is economically feasible, compared with a system with free enzymes, despite a very high cost for the enzyme attachment. At a half-life time of 80 d, the PFTR gives the lowest cost (0.48 SEK/kg lactose), but the cost for the BTRI is just slightly higher (0.66 SEK/kg lactose) and still much lower than the BTRF (2.10 SEK/kg lactose).
Enzyme immobilization is economically feasible, compared with a system with free enzymes, despite a very high cost for the enzyme attachment. At a half-life time of 80 d, the PFTR gives the lowest cost (0.48 SEK/kg lactose), but the cost for the BTRI is just slightly higher (0.66 SEK/kg lactose) and still much lower than the BTRF (2.10 SEK/kg lactose).
Department/s
Publishing year
1990
Language
English
Pages
679-693
Publication/Series
Applied Biochemistry and Biotechnology
Volume
24-5
Document type
Journal article
Publisher
Humana Press
Topic
- Biochemistry and Molecular Biology
Status
Published
ISBN/ISSN/Other
- ISSN: 1559-0291