Brain matrix: structure, turnover and necessity.

Summary, in English

Aided by mice with multiple deleted brain matrix protein genes, the biochemical analysis of mouse brain matrix molecules indicates a constitutive production of more proteoglycans than can be integrated in multimolecular matrix structures. Possible functions of non-matrix integrated proteoglycans, and aspects of incomplete compensatory mechanisms in knockout mice are discussed.

• Author: Uwe Rauch
• Department/s: Vessel Wall Biology
• Publishing year: 2007
• Language: English
• Pages: 656-660
• Publication/Series: Biochemical Society Transactions
• Volume: 35
• Issue: 4
• Links: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17635114&dopt=Abstract; http://www.biochemsoctrans.org/bst/035/bst0350656.htm
• Document type: Journal article
• Publisher: Biochemical Society
• Topic: Biochemistry and Molecular Biology
• Keywords: Brain matrix; structure; turnover
• Status: Published
• Research group: Vessel Wall Biology
• ISBN/ISSN/Other: ISSN: 0300-5127