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Novel properties of antimicrobial peptides

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Author

  • Wojciech Kamysz
  • Marcin Okroj
  • Jerzy Lukasiak

Summary, in English

Endogenous peptide antibiotics are known as evolutionarily old components of innate immunity. Due to interaction with cell membrane these peptides cause permeabilization of the membrane and lysis of invading microbes. However, some studies proved that antimicrobial peptides are universal multifunctional molecules and their functions extend far beyond simple antibiotics. In this review we present an overview of the general mechanism of action of antimicrobial peptides and discuss some of their additional properties, like antitumour activity, mitogenic activity, role in signal transduction pathways and adaptive immune response.

Publishing year

2003

Language

English

Pages

461-469

Publication/Series

Acta Biochimica Polonica

Volume

50

Issue

2

Document type

Journal article review

Publisher

Panstwowe Wydawnictwo Naukowe

Topic

  • Other Basic Medicine

Status

Published

ISBN/ISSN/Other

  • ISSN: 0001-527X