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Do leukotrienes increase cell viability in human intestinal epithelial cells?

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Author

Summary, in English

In this preliminary report we present data showing that leukotrienes increase the baseline cell viability in human intestinal epithelial cells and that LTB4 partially reverses the morphological hallmarks of non-necrotic cell death induced by the COX-2 specific inhibitor NS-398. The proposed signaling mechanisms regulating these events are summarized in fig. 3. Please view the work on LT signal transduction in these cells by Thodeti et al. in this volume.

Publishing year

2002

Language

English

Pages

193-198

Publication/Series

Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation, and Radiation Injury, 5 (Advances in Experimental Medicine and Biology)

Volume

507

Document type

Book chapter

Publisher

Springer

Topic

  • Cancer and Oncology

Status

Published

Research group

  • Experimental Pathology, Malmö

ISBN/ISSN/Other

  • ISSN: 0065-2598
  • ISBN: 978-0-306-47283-1