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First-trimester diagnosis on chorionic villi obtained by direct vision technique

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Author

Summary, in English

An improved technique for direct vision chorionic biopsy that gives a clear view of the amniotic sac was developed. With this technique, used in 48 women prior to vacuum aspiration and in six cases for diagnosis (karyotyping or enzyme analysis), it was possible to obtain chorionic villi free from contamination by maternal tissue. It was also possible to pick out villi (rich in blood vessels and with abundant buds on their surface) found to be most capable of growing in vitro. In the diagnostic cases, the pregnancies have continued uneventfully since the sampling; one pregnancy is now in the 32nd week.

Publishing year

1984

Language

English

Pages

373-376

Publication/Series

Human Genetics

Volume

65

Issue

4

Document type

Journal article

Publisher

Springer

Topic

  • Medical Genetics

Status

Published

ISBN/ISSN/Other

  • ISSN: 1432-1203