P¹/P² genotyping of known and novel null alleles in the P1PK and GLOB histo-blood group systems.

Summary, in English

The rare but clinically important null phenotypes of the P1PK and GLOB blood group systems are due to alterations in A4GALT and B3GALNT1, respectively. A recently identified single-nucleotide polymorphism in Exon 2a of A4GALT predicts the common P1 and P2 phenotypes but rare variants have not been tested.

• Author: Julia Westman; Åsa Hellberg; Thierry Peyrard; Hein Hustinx; Britt Thuresson; Martin L Olsson
• Department/s: Division of Hematology and Transfusion Medicine; Transfusion Medicine
• Publishing year: 2013
• Language: English
• Pages: 2928-2939
• Publication/Series: Transfusion
• Volume: 53
• Issue: 11
• Links: http://www.ncbi.nlm.nih.gov/pubmed/23927681?dopt=Abstract; http://dx.doi.org/10.1111/trf.12355
• Document type: Journal article
• Publisher: Wiley-Blackwell
• Topic: Hematology
• Status: Published
• Research group: Transfusion Medicine
• ISBN/ISSN/Other: ISSN: 1537-2995