Sortilin expression is essential for pro-nerve growth factor-induced apoptosis of rat vascular smooth muscle cells.

Summary, in English

Sortilin, a member of the Vps10p-domain receptor family, has been demonstrated a key regulator in mediating cellular response to pro-neurotrophins. In the present study, we investigated the role of sortilin in the apoptotic pathway of vascular smooth muscle cells.

• Author: Luisa Campagnolo; Gaetana Costanza; Arianna Francesconi; Gaetano Arcuri; Ilana Moscatelli; Augusto Orlandi
• Department/s: Division of Molecular Medicine and Gene Therapy
• Publishing year: 2014
• Language: English
• Publication/Series: PLoS ONE
• Volume: 9
• Issue: 1
• Full text: - 2 MB; Download statistics
• Links: http://www.ncbi.nlm.nih.gov/pubmed/24404198?dopt=Abstract; http://dx.doi.org/10.1371/journal.pone.0084969
• Document type: Journal article
• Publisher: Public Library of Science (PLoS)
• Topic: Hematology
• Status: Published
• ISBN/ISSN/Other: ISSN: 1932-6203