Computational Perspectives on Neuromodulation of Aging
Author
Summary, in English
Cognitive functions, such as memory, attention, and perception, declines with age. Besides other neuroanatomical changes, the level of dopamine also attenuates during aging. We review how computational modeling can provide insights in how these lifetime changes in dopamine levels is expressed at the behavioral level yielding a bridge across different levels. Results indicate that attenuation of dopamine lowers the signal to noise ratio providing a less distinctive neural representation, and detrimental cognitive performance.
Department/s
Publishing year
2007
Language
English
Pages
513-518
Publication/Series
Acta Neurochirurgica. Supplementum
Volume
97
Document type
Journal article review
Publisher
Springer
Topic
- Psychology (excluding Applied Psychology)
Keywords
- cognitive functions
- neural networks
- aging
- neuromodulation
- Dopamine
- noise
Status
Published
Research group
- Lund University Cognitive Science (LUCS)
ISBN/ISSN/Other
- ISSN: 0065-1419