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Spasmolytic flavonols from Artemisia abrotanum

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Author

Summary, in English

Four flavonols with spasmolytic activity have been isolated from a methanol extract of Artemisia abrotanum L. (Asteraceae), as the principles primarily responsible for the smooth muscle relaxing activity of this plant. The flavonols show a dose-dependent relaxing effect on the carbacholine-induced contraction of guinea-pig trachea, the EC50 values for compounds 1-3 are 20-30 mumol/l while compound 4 is less active.

Publishing year

1995

Language

English

Pages

370-371

Publication/Series

Planta Medica

Volume

61

Issue

4

Document type

Journal article

Publisher

Georg Thieme Verlag

Topic

  • Dermatology and Venereal Diseases

Status

Published

ISBN/ISSN/Other

  • ISSN: 0032-0943