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2-Bromoethyl glycosides for synthesis of glycoconjugates on solid support

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Author

Summary, in English

2-Bromoethyl glycosides can easily and in high yields be transformed into sulfones by treatment with a suitable thiol followed by oxidation with mCPBA. The observation that the so formed sulfones were cleaved by treatment with NaOMe/MeOH was used to design a new safety catch linker for synthesis of glycoconjugates on solid support. (C) 2005 Elsevier Ltd. All rights reserved.

Publishing year

2005

Language

English

Pages

2421-2429

Publication/Series

Tetrahedron

Volume

61

Issue

9

Document type

Journal article

Publisher

Elsevier

Topic

  • Organic Chemistry

Status

Published

ISBN/ISSN/Other

  • ISSN: 0040-4020