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Oligomeric acylphloroglucinols from myrtle (Myrtus communis)

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Author

  • G Appendino
  • F Bianchi
  • A Minassi
  • Olov Sterner
  • M Ballero
  • S Gibbons

Summary, in English

The dimeric nonprenylated acylphloroglucinol semimyrtucommulone (6) was obtained from the leaves of. myrtle (Myrtus communis) as a 2:1 mixture of two rotamers. The known trimeric phloroglucinol myrtucommulone A (1) was also isolated and characterized spectroscopically as a silylated cyclized derivative (5). Myrtucommulone A showed significant antibacterial activity against multidrug-resistant (MDR) clinically relevant bacteria, while semimyrtucommulone was less active.

Publishing year

2002

Language

English

Pages

334-338

Publication/Series

Journal of Natural Products

Volume

65

Issue

3

Document type

Journal article

Publisher

The American Chemical Society (ACS)

Topic

  • Organic Chemistry

Status

Published

ISBN/ISSN/Other

  • ISSN: 0163-3864