New peptaibols from Mycogone cervina

Summary, in English

From cultures of Mycogone cervina, a mycophilic fungus growing on the fruit bodies of ascomycete Paxina acetabulum, two new peptaibols (cervinin, N-Ac-Leu-Aib-Pro-Aib-Leu-Aib-Pro-Ala-Aib-Pro-Val-red-Leu (1) and the red-Leu O-acetylated derivative 2) were isolated. The structures of 1 and 2 were elucidated by spectroscopic techniques. They exhibited weak antibacterial as well as cytotoxic activities. They are the first secondary metabolites described from M. cervina.

• Author: C Wilhelm; H Anke; Yonny Flores; Olov Sterner
• Department/s: Centre for Analysis and Synthesis
• Publishing year: 2004
• Language: English
• Pages: 466-468
• Publication/Series: Journal of Natural Products
• Volume: 67
• Issue: 3
• Links: http://dx.doi.org/10.1021/np0302899
• Document type: Journal article
• Publisher: The American Chemical Society (ACS)
• Topic: Organic Chemistry
• Status: Published
• ISBN/ISSN/Other: ISSN: 0163-3864