High Plasma Levels of Galectin-3 Are Associated with Increased Risk for Stroke after Carotid Endarterectomy.

Summary, in English

Galectin-3 (Gal-3) has been suggested to have both pro- and anti-atherogenic properties. High plasma Gal-3 levels are associated with increased risk for cardiovascular (CV) death. However, it has so far not been investigated if plasma Gal-3 levels can predict the risk for future stroke in patients suffering from carotid atherosclerosis. The aim of this study was to investigate whether Gal-3 could be used as a marker to predict postoperative cerebrovascular ischemic events among patients who underwent carotid endarterectomy (CEA).

• Author: Andreas Edsfeldt; Eva Bengtsson; Giuseppe Asciutto; Pontus Dunér; Harry Björkbacka; Gunilla Nordin Fredrikson; Jan Nilsson; Isabel Goncalves
• Department/s: EXODIAB: Excellence of Diabetes Research in Sweden; EpiHealth: Epidemiology for Health; Cardiovascular Research - Immunity and Atherosclerosis; Cardiovascular Research - Translational Studies
• Publishing year: 2016
• Language: English
• Pages: 199-203
• Publication/Series: Cerebrovascular Diseases
• Volume: 41
• Issue: 3-4
• Links: http://www.ncbi.nlm.nih.gov/pubmed/26812165?dopt=Abstract; http://dx.doi.org/10.1159/000443022
• Document type: Journal article
• Publisher: Karger
• Topic: Cardiac and Cardiovascular Systems
• Status: Published
• Research group: Cardiovascular Research - Immunity and Atherosclerosis; Cardiovascular Research - Translational Studies
• ISBN/ISSN/Other: ISSN: 1421-9786