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Plasma levels of apolipoprotein M in normal and complicated pregnancy.

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Author

Summary, in English

Apolipoprotein M (apoM) is mainly associated with high-density lipoprotein in human plasma. Despite several studies suggesting apoM as an anti-atherogenic, its function is not yet fully understood. Plasma apoM was measured in normal pregnancies at four different gestational ages and in the postpartum period to investigate whether the concentration of apoM changes during pregnancy. In addition, apoM was measured at 13 weeks in women who subsequently developed preeclampsia, gestational diabetes, recurrent miscarriage, or small-for-gestational age babies, and in women with uncomplicated pregnancies. The plasma concentrations of apoM increased during pregnancy to reach highest levels in the postpartum period. Thus, plasma apoM in non-pregnant women was around 0.77 micromol/l, 0.88 micromol/l at 40 gestational weeks, and 1.05 micromol/l in the postpartum period (p < 0.0001). No differences in plasma concentrations of apoM were found among the studied pregnancy complications.

Publishing year

2010

Language

English

Pages

1214-1217

Publication/Series

Acta Obstetricia et Gynecologica Scandinavica

Volume

89

Issue

9

Document type

Journal article

Publisher

Wiley-Blackwell

Topic

  • Obstetrics, Gynecology and Reproductive Medicine

Keywords

  • Pregnancy Complications: blood
  • Pregnancy: blood
  • Apolipoproteins: blood
  • Postpartum Period: blood

Status

Published

Research group

  • Clinical Chemistry, Malmö

ISBN/ISSN/Other

  • ISSN: 1600-0412