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Suicidal patients are deficient in vitamin D, associated with a pro-inflammatory status in the blood.

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Author

Summary, in English

Low levels of vitamin D may play a role in psychiatric disorders, as cross-sectional studies show an association between vitamin D deficiency and depression, schizophrenia and psychotic symptoms. The underlying mechanisms are not well understood, although vitamin D is known to influence the immune system to promote a T helper (Th)-2 phenotype. At the same time, increased inflammation might be of importance in the pathophysiology of depression and suicide. We therefore hypothesized that suicidal patients would be deficient in vitamin D, which could be responsible for the inflammatory changes observed in these patients.

Publishing year

2014

Language

English

Pages

210-219

Publication/Series

Psychoneuroendocrinology

Volume

50

Document type

Journal article

Publisher

Elsevier

Topic

  • Medicinal Chemistry
  • Psychiatry

Status

Published

Project

  • Individanpassad behandling av patienter med depression, med särskilt fokus på suicidrisk.

Research group

  • Clinical Chemistry, Malmö
  • Unit for clinical suicide research

ISBN/ISSN/Other

  • ISSN: 1873-3360