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Characterization of genetic variation in TLR8 in relation to allergic rhinitis.

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Author

  • V Henmyr
  • C Lind-Halldén
  • D Carlberg
  • C Halldén
  • E Melén
  • M Wickman
  • A Bergström
  • Torbjörn Säll
  • L O Cardell

Summary, in English

A previous investigation of all 10 TLR-genes for associations with allergic rhinitis (AR) detected a number of significant SNPs in the TLR8 locus. The associations indicated that an accumulation of rare variants could explain the signal. The present study therefore searches for rare variants in the TLR8 region and also investigates the reproducibility of previous SNP associations.

Publishing year

2015-12-02

Language

English

Publication/Series

Allergy

Document type

Journal article

Publisher

Wiley-Blackwell

Topic

  • Respiratory Medicine and Allergy
  • Medical Genetics

Status

Published

ISBN/ISSN/Other

  • ISSN: 1398-9995