GWAS-identified loci for coronary heart disease are associated with intima-media thickness and plaque presence at the carotid artery bulb.

Summary, in English

Large-scale genome-wide association studies (GWAS) have so far identified 45 loci that are robustly associated with coronary heart disease (CHD) in data from adult men and women of European descent.

• Author: Marcel den Hoed; Rona J Strawbridge; Peter Almgren; Stefan Gustafsson; Tomas Axelsson; Gunnar Engström; Ulf de Faire; Bo Hedblad; Steve E Humphries; Cecilia M Lindgren; Andrew P Morris; Gerd Östling; Ann-Christine Syvänen; Elena Tremoli; Anders Hamsten; Erik Ingelsson; Olle Melander; Lars Lind
• Department/s: Translational Muscle Research; Cardiovascular Research - Epidemiology; Cardiovascular Research - Immunity and Atherosclerosis; Cardiovascular Research - Hypertension; EXODIAB: Excellence of Diabetes Research in Sweden; EpiHealth: Epidemiology for Health
• Publishing year: 2015
• Language: English
• Pages: 304-310
• Publication/Series: Atherosclerosis
• Volume: 239
• Issue: 2
• Links: http://www.ncbi.nlm.nih.gov/pubmed/25682028?dopt=Abstract; http://dx.doi.org/10.1016/j.atherosclerosis.2015.01.032
• Document type: Journal article
• Publisher: Elsevier
• Topic: Cardiac and Cardiovascular Systems
• Status: Published
• Research group: Genomics, Diabetes and Endocrinology; Cardiovascular Research - Epidemiology; Cardiovascular Research - Immunity and Atherosclerosis; Cardiovascular Research - Hypertension
• ISBN/ISSN/Other: ISSN: 1879-1484