Impaired Fibrous Repair: A Possible Contributor to Atherosclerotic Plaque Vulnerability in Patients With Type II Diabetes.

Summary, in English

Diabetes mellitus (DM) type II is increasing rapidly worldwide. Patients with DM II have a greater atherosclerotic burden and higher risk of developing cardiovascular complications. Inflammation has been proposed as the main cause for the high risk of atherosclerotic disease in DM II. In this study, we compared markers of inflammation and fibrous repair in plaques from subjects with and without DM II.

• Author: Andreas Edsfeldt; Isabel Goncalves; Helena Grufman; Mihaela Nitulescu; Pontus Dunér; Eva Bengtsson; Ines Mollet; Ana Persson; Marie MN Nilsson; Marju Orho-Melander; Olle Melander; Harry Björkbacka; Jan Nilsson
• Department/s: EXODIAB: Excellence of Diabetes Research in Sweden; EpiHealth: Epidemiology for Health; Cardiovascular Research - Immunity and Atherosclerosis; Cardiovascular Research - Translational Studies; Diabetes - Islet Cell Exocytosis; Diabetes - Cardiovascular Disease; Cardiovascular Research - Hypertension
• Publishing year: 2014
• Language: English
• Pages: 2143-2150
• Publication/Series: Arteriosclerosis, Thrombosis and Vascular Biology
• Volume: 34
• Issue: 9
• Links: http://www.ncbi.nlm.nih.gov/pubmed/25035341?dopt=Abstract; http://dx.doi.org/10.1161/ATVBAHA.114.303414
• Document type: Journal article
• Publisher: Lippincott Williams & Wilkins
• Topic: Cardiac and Cardiovascular Systems
• Status: Published
• Research group: Cardiovascular Research - Immunity and Atherosclerosis; Cardiovascular Research - Translational Studies; Diabetes - Islet Cell Exocytosis; Diabetes - Cardiovascular Disease; Cardiovascular Research - Hypertension
• ISBN/ISSN/Other: ISSN: 1524-4636