Cardiovascular consequences of a polygenetic component of blood pressure in an urban-based longitudinal study: the Malmö Diet and Cancer.
Author
Summary, in English
A recently published genome wide association study identified 29 single nucleotide polymorphisms (SNPs) influencing blood pressure (BP). Case-control studies suggest that a genetic risk score (GRS) based on these 29 SNPs affect the risk of cardiovascular disease (CVD), but its role for CVD at population level is unknown. Here, we prospectively evaluate the impact of this polygenetic BP component on CVD morbidity and mortality in a large urban-based middle-aged population.
Department/s
Publishing year
2014
Language
English
Pages
1424-1428
Publication/Series
Journal of Hypertension
Volume
32
Issue
7
Links
Document type
Journal article
Publisher
Lippincott Williams & Wilkins
Topic
- Cardiac and Cardiovascular Systems
Status
Published
Project
- Genetic causes and prediction of hypertension
Research group
- Genomics, Diabetes and Endocrinology
- Cardiovascular Research - Hypertension
- Cardiovascular Research - Epidemiology
- Internal Medicine - Epidemiology
ISBN/ISSN/Other
- ISSN: 1473-5598