Extensive changes in the transcriptional profile of human adipose tissue including genes involved in oxidative phosphorylation after a six months exercise intervention.
Author
Summary, in English
Adipose tissue has an important function in total energy homeostasis and its dysregulation may contribute to life-style related diseases such as type 2 diabetes, cancer and cardiovascular diseases. The aim of this study was to investigate genome-wide mRNA expression in adipose tissue in healthy men before and after an exercise intervention to identify genes or pathways that mediate the beneficial effect of regular exercise. We also investigated the difference in adipose tissue mRNA expression between individuals with or without a family history of type 2 diabetes.
Department/s
Publishing year
2014
Language
English
Pages
188-200
Publication/Series
Acta Physiologica
Volume
211
Issue
1
Links
Document type
Journal article
Publisher
Wiley-Blackwell
Topic
- Physiology
Status
Published
Project
- Fysik aktivitet, träning och kost vid typ 2 diabetes
Research group
- Genomics, Diabetes and Endocrinology
- Diabetes - Epigenetics
- Human Movement: health and rehabilitation
- Vascular Diseases - Clinical Research
ISBN/ISSN/Other
- ISSN: 1748-1716