Using genetics to test the causal relationship of total adiposity and periodontitis: Mendelian randomization analyses in the Gene-Lifestyle Interactions and Dental Endpoints (GLIDE) Consortium.

Summary, in English

The observational relationship between obesity and periodontitis is widely known, yet causal evidence is lacking. Our objective was to investigate causal associations between periodontitis and body mass index (BMI).

• Author: Dmitry Shungin; Marilyn C Cornelis; Kimon Divaris; Birte Holtfreter; John R Shaffer; Yau-Hua Yu; Silvana P Barros; James D Beck; Reiner Biffar; Eric A Boerwinkle; Richard J Crout; Andrea Ganna; Goran Hallmans; George Hindy; Frank B Hu; Peter Kraft; Daniel W McNeil; Olle Melander; Kevin L Moss; Kari E North; Marju Orho-Melander; Nancy L Pedersen; Paul M Ridker; Eric B Rimm; Lynda M Rose; Gull Rukh; Alexander Teumer; Robert J Weyant; Daniel I Chasman; Kaumudi Joshipura; Thomas Kocher; Patrik Ke Magnusson; Mary L Marazita; Peter Nilsson; Steve Offenbacher; George Davey Smith; Pernilla Lundberg; Tom M Palmer; Nicholas J Timpson; Ingegerd Johansson; Paul Franks
• Department/s: EXODIAB: Excellence of Diabetes Research in Sweden; EpiHealth: Epidemiology for Health; Genetic and Molecular Epidemiology; Diabetes - Cardiovascular Disease; Cardiovascular Research - Hypertension; Internal Medicine - Epidemiology
• Publishing year: 2015
• Language: English
• Pages: 638-650
• Publication/Series: International Journal of Epidemiology
• Volume: 44
• Issue: 2
• Links: http://www.ncbi.nlm.nih.gov/pubmed/26050256?dopt=Abstract; http://dx.doi.org/10.1093/ije/dyv075
• Document type: Journal article
• Publisher: Oxford University Press
• Topic: Public Health, Global Health, Social Medicine and Epidemiology
• Status: Published
• Research group: Genetic and Molecular Epidemiology; Diabetes - Cardiovascular Disease; Cardiovascular Research - Hypertension; Internal Medicine - Epidemiology
• ISBN/ISSN/Other: ISSN: 1464-3685